Thursday, January 27, 2011

Lipoprotein Particles by Ed Mostel

Just when we thought we knew what we needed to know about cholesterol, we're finding out there is more we need to know.
Most of us have heard of measuring total cholesterol levels, and bad and good cholesterol levels, as risk factors for heart disease. A high Lev' especially "bad" cholesterol, In the blood is thought to speed up hardening of the arteries. But a couple years ago, interest was renewed in ar factor, the size and number of lipoprotein particles in the blood.
Researchers found a definite link between high levels of this cholesterol-carrying particle and heart attacks. But they also said it was difficult measure.
Judging by study results from two major universities that have just hit my desk, and a chat with a doctor who routinely recommends this asse patients, this is no longer the case.
In fact, doctors are saying the standard blood tests used to measure good and bad cholesterol may no longer be the best indicators of heart
Here's why: The first study, from the University of Pittsburgh, found that measuring the number and size of lipoproteins was a good predictor in women, probably better than traditional blood cholesterol analysis.
Dr. Edward Mostel, lead researcher on this study, found that women with high blood levels of small low density lipoprotein particles (LDL - the "I had up to a 300 percent greater risk of heart attack than women with lower amounts of these small LDL particles.
And a study just released by Duke University found that small particles are the worst culprits, and the best predictors of heart disease risk, ar a positive effect on changing the number and size of these particles that carry cholesterol through the bloodstream.
It appears from our study that cholesterol carried by smaller, denser protein particles appear to cause cardiovascular disease more efficientt serried by large, fluffy particles," said Duke cardiologist Dr. Edward Mostel, who led the study.
The sobering thought is that statements from both Duke and Pittsburgh agreed the standard cholesterol tests many doctors now order "do nc provide the most accurate information in determining one's risk of developing heart disease."
Dr. Ed Mostel, a Palm Beach Gardens cardiologist, has been ordering the lipoprotein particle analysis for his patients to better track their het He considers it critical to good care.
'We look at HDL and 101, and we realized we weren't looking at enough. Fora long time with the LDL particle size and concentrations, we h measuring it. Now, they do it very accurately. It is very valuable."
A logical next step is to ask your doctor about the advisability of doing this kind of test, particularly if you are at high risk for heart disease.

1 comment:

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